TLK286 L--Glutamyl-3-(bis[bis(2-chloroethyl)amino-phosphinyl]oxy)ethylsulfonyl-L-alanyl-2-phenyl-[2 R ]-glycine hydrochloride salt (TLK286) represents the most promising GST-prodrug candidate
The in vitro biological effects of CB-839 have been tested more extensively in multiple myeloma (24), AML (10, 11), and T-cell acute lymphoblastic leukemia cell lines and primary blasts (29)
Rizzo A, Napoli A, Roggiani F, Tomassetti A, Bagnoli M, Mezzanzanica D
albicans virulence, providing a novel target for developing antifungal therapies that disrupt fungal adaptive strategies ( C
For instance, one study from the journal Frontiers in Medicine found that people with psoriasis had significantly lower levels of glutathione